PFK-015 is a potent and selective inhibitor of receptor-interacting protein kinase 1 (RIPK1), a key enzyme in necroptosis and inflammatory signaling pathways. It is primarily used in research settings to study and understand the mechanisms of RIPK1 and related kinases, which play crucial roles in cellular signaling, inflammation, and cell death. By inhibiting specific kinase activities, it helps scientists investigate the effects on cell growth, proliferation, survival, and inflammatory responses, contributing to advancements in understanding diseases like cancer, neurodegenerative disorders, and inflammatory conditions. Additionally, it serves as a tool in drug discovery, aiding in the development of targeted therapies by providing insights into the regulation of key biological processes. Its application is limited to laboratory studies and is not used in clinical or industrial contexts.