BRD7389 is primarily used in research settings as a potent and selective inhibitor of p90 ribosomal S6 kinase (RSK). It is particularly valuable in studying cellular signaling pathways, especially those involving the MAPK/ERK cascade, which plays a critical role in cell proliferation, survival, and differentiation. By inhibiting RSK, BRD7389 helps researchers understand the biological functions of RSK isoforms and their contribution to diseases such as cancer, where RSK activity is often dysregulated. Additionally, it is utilized in drug discovery efforts to explore potential therapeutic strategies targeting RSK-dependent pathways. Its application extends to studying mechanisms of cell migration, apoptosis, and stress responses, providing insights into both normal physiology and pathological conditions.