GNF4877 is primarily utilized in the field of biomedical research, particularly in the study of neurodegenerative diseases. It functions as a potent and selective inhibitor of the RIP1 kinase enzyme, which plays a critical role in regulating cell death and inflammation. This makes it a valuable tool for investigating pathways involved in conditions such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Researchers use GNF4877 to explore potential therapeutic strategies aimed at modulating cell survival and inflammatory responses, offering insights into the development of novel treatments for these disorders.