CAY10648 is primarily used in research settings as a selective inhibitor of sphingosine kinase 2 (SphK2). This enzyme plays a crucial role in the sphingolipid metabolism pathway, which is involved in various cellular processes, including cell growth, survival, and inflammation. By inhibiting SphK2, CAY10648 helps scientists study the effects of sphingolipid signaling in diseases such as cancer, inflammation, and metabolic disorders. It is particularly valuable in understanding the role of SphK2 in cancer progression, as it allows researchers to explore potential therapeutic targets. Additionally, CAY10648 is used in preclinical studies to investigate its potential as a treatment for conditions where dysregulated sphingolipid metabolism is implicated.