WYE-125132 (WYE-132) is a potent and selective inhibitor of mTOR (mammalian target of rapamycin) kinase, primarily used in research settings to study its effects on mTOR-dependent biological pathways. It is often employed in preclinical studies to investigate its potential as a therapeutic agent, particularly in targeting mTOR involved in disease mechanisms such as cancer proliferation, metabolic regulation, and inflammation. Researchers utilize this compound to explore its efficacy and safety profile in cellular and animal models, aiming to understand its pharmacological properties. Its application is crucial in advancing knowledge in drug discovery and development, particularly in areas like oncology and metabolic disorders, where targeted mTOR inhibition is essential.