Tyrosine kinase inhibitors are primarily used in the treatment of various cancers. They work by blocking the action of tyrosine kinases, enzymes that play a key role in the signaling pathways that drive cancer cell growth and proliferation. These inhibitors are particularly effective in targeting specific types of cancer, such as chronic myeloid leukemia (CML), non-small cell lung cancer (NSCLC), and certain forms of breast cancer. By inhibiting these enzymes, the drugs help to slow down or stop the growth of cancer cells, leading to improved patient outcomes. Additionally, they are often used in combination with other therapies, such as chemotherapy or radiation, to enhance overall treatment efficacy. Some tyrosine kinase inhibitors are also being explored for their potential in treating other conditions, including inflammatory diseases and certain types of autoimmune disorders, due to their ability to modulate immune responses.