SB 202190 is widely used in biochemical research as a potent and selective inhibitor of p38 MAP kinase. It plays a crucial role in studying cellular signaling pathways, particularly those involved in inflammation, stress responses, and apoptosis. Researchers utilize it to investigate the mechanisms of cytokine production and the regulation of immune responses. Additionally, it is employed in preclinical studies to explore potential therapeutic interventions for inflammatory diseases, such as rheumatoid arthritis and chronic obstructive pulmonary disease (COPD). Its ability to modulate p38 MAP kinase activity makes it a valuable tool for understanding cell behavior under stress conditions and for developing targeted treatments.