PF-06459988 is primarily utilized in the field of pharmaceutical research and development. It serves as a potent and selective inhibitor of certain kinases, making it a valuable tool in studying cellular signaling pathways. Its application is particularly significant in cancer research, where it helps in understanding the mechanisms of tumor growth and progression. By inhibiting specific kinases, it aids in identifying potential therapeutic targets for various cancers. Additionally, it is used in preclinical studies to evaluate the efficacy and safety of new cancer treatments. Its role in these studies contributes to the development of novel drugs that could improve patient outcomes in oncology.