IQ-1S free acid is primarily used in biochemical research, particularly in the study of cellular signaling pathways. It is known for its role as an inhibitor of the JNK (c-Jun N-terminal kinase) pathway, which is involved in various cellular processes such as apoptosis, inflammation, and stress responses. Researchers utilize IQ-1S free acid to investigate the mechanisms of these pathways and to explore potential therapeutic applications in diseases where JNK signaling is dysregulated, such as cancer, neurodegenerative disorders, and inflammatory conditions. Its application helps in understanding the molecular basis of these diseases and in the development of targeted treatments.