DMH1 is widely used in research settings to study the BMP (bone morphogenetic protein) signaling pathway, which plays a critical role in cellular processes such as differentiation, proliferation, and apoptosis. It is particularly valuable in inhibiting BMP type I receptors, specifically ALK2, making it a useful tool for investigating bone and cartilage development, as well as diseases related to abnormal BMP signaling. Researchers also utilize DMH1 in stem cell studies to control differentiation pathways, aiding in the development of potential therapeutic strategies for conditions like osteoporosis or cancer. Additionally, it is employed in organoid and tissue engineering research to better understand tissue regeneration and repair mechanisms.