CRT0066101 is primarily used in research settings to study its potential as an inhibitor of protein kinase D (PKD). It has shown promise in preclinical studies for its role in modulating cellular processes such as cell proliferation, migration, and survival. Researchers are exploring its application in cancer therapy, particularly in targeting cancers where PKD signaling is dysregulated. Additionally, it is being investigated for its potential to inhibit angiogenesis, which could be beneficial in treating conditions like tumor growth and certain inflammatory diseases. Its use remains experimental, with ongoing studies to determine efficacy and safety in therapeutic contexts.