CGP 57380 is primarily used in biochemical research to study cellular signaling pathways. It acts as an inhibitor of MNK1, a kinase involved in the regulation of protein synthesis. Researchers utilize this compound to investigate its effects on cancer cell proliferation and survival, as MNK1 plays a role in tumor progression. Additionally, it is employed to explore potential therapeutic strategies targeting MNK1 in diseases like leukemia and solid tumors. Its application extends to understanding the molecular mechanisms underlying inflammation and immune responses, as MNK1 is also implicated in these processes.