1-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-(propan-2-yl)urea

95%

Reagent Code: #80023
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CAS Number 2246769-29-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 322.1828 g/mol
Formula C₁₆H₂₄BFN₂O₃
badge Registry Numbers
MDL Number MFCD32206475
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of kinase inhibitors. Its structure, featuring a dioxaborolane group, makes it a valuable intermediate in Suzuki-Miyaura cross-coupling reactions, which are widely employed in the synthesis of complex organic molecules, including pharmaceuticals. The fluorine atom enhances its binding affinity to target proteins, while the urea moiety contributes to its ability to form hydrogen bonds, improving its interaction with biological targets. This chemical is often explored in the design of drugs targeting cancer, inflammation, and other diseases where kinase modulation is therapeutic. Its application in drug discovery is driven by its potential to improve selectivity and efficacy in inhibiting specific kinases.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿10,998.00
inventory 25mg
10-20 days ฿3,672.00

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