6-[5-[[[2-(Methyl-d3-sulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine
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This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of targeted therapeutic agents, particularly in the development of kinase inhibitors. These inhibitors are designed to modulate specific signaling pathways involved in diseases such as cancer, where aberrant kinase activity often drives tumor growth and progression. The compound's structure, featuring a quinazoline core and a triazolopyridine moiety, is tailored to enhance binding affinity and selectivity toward certain kinase targets. Researchers leverage its properties to optimize pharmacokinetic profiles and improve the efficacy of potential drug candidates. Additionally, its deuterated methyl group can contribute to metabolic stability, making it a valuable component in the design of deuterated drugs, which often exhibit enhanced bioavailability and reduced toxicity.
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