UCN-01 is primarily investigated for its potential in cancer therapy due to its ability to inhibit protein kinases, particularly those involved in cell cycle regulation. It has shown promise in enhancing the efficacy of chemotherapy and radiation by disrupting cancer cell survival mechanisms. Additionally, UCN-01 is being studied for its role in overcoming drug resistance in certain cancers, making it a valuable candidate for combination therapies. Its unique mechanism of action also positions it as a potential treatment for other diseases involving abnormal cell proliferation.