1-(4-(Trifluoromethyl)phenyl)prop-2-yn-1-one
98%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors, anti-inflammatory agents, antimicrobials, antivirals, and other biologically active compounds. The trifluoromethyl group enhances metabolic stability, lipophilicity, and cell membrane permeability, making it ideal for intracellularly acting drugs. Its alkyne and ketone functional groups enable versatile reactivity, especially in click chemistry and palladium-catalyzed coupling reactions. Commonly employed in medicinal chemistry for constructing heterocyclic compounds and bioactive molecules. Also utilized in agrochemical research for designing novel pesticides with improved stability and efficacy, and in biomaterials.
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