2',3',4',5'-Tetrafluoroacetophenone
98%
Reagent
Code: #239992
CAS Number
66286-21-3
blur_circular Chemical Specifications
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Molecular Information
Weight
192.11 g/mol
Formula
C₈H₄F₄O
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Registry Numbers
MDL Number
MFCD00134310
thermostat
Physical Properties
Boiling Point
83-84 °C20 mm Hg(lit.)
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Storage & Handling
Density
1.408 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine atoms enhance metabolic stability and bioavailability. Its structure allows for selective functionalization, making it valuable in creating analogs for drug discovery. Also employed in the preparation of agrochemicals and specialty materials requiring high thermal and oxidative stability. Commonly utilized in cross-coupling reactions and nucleophilic additions to build complex aromatic compounds in research and industrial settings.
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