4-Fluorobenzoylacetic acid methyl ester
98%
Reagent
Code: #187162
CAS Number
63131-29-3
science Other reagents with same CAS 63131-29-3
blur_circular Chemical Specifications
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Molecular Information
Weight
196.18 g/mol
Formula
C₁₀H₉FO₃;FC₆H₄COCH₂CO₂CH₃
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Registry Numbers
EC Number
263-889-6
MDL Number
MFCD00000355
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Physical Properties
Boiling Point
91°C/5mm
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Storage & Handling
Density
1.228 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where fluorinated aromatic compounds enhance metabolic stability and bioavailability. It serves as a building block in the preparation of ketoprofen derivatives and other nonsteroidal anti-inflammatory drugs (NSAIDs). The ester functionality allows for easy modification in multi-step organic syntheses, making it valuable in medicinal chemistry for constructing complex molecules. Also employed in the production of agrochemicals and specialty polymers due to the electron-withdrawing nature of the fluorine atom, which influences reactivity and material properties.
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