2'-Fluoropropiophenone
98%
Reagent
Code: #187091
Alias
2-Fluorophenylacetone;O-fluorophenylacetone, 2-Fluorophenylethylketone
CAS Number
446-22-0
blur_circular Chemical Specifications
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Molecular Information
Weight
152.17 g/mol
Formula
C₉H₉FO
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Registry Numbers
MDL Number
MFCD00009893
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Physical Properties
Boiling Point
95-99 °C19 mm Hg(lit.)
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Storage & Handling
Density
1.102 g/mL at 25 °C(lit.)
Storage
-20°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of central nervous system (CNS) active compounds. It serves in the development of selective serotonin reuptake inhibitors (SSRIs) and other antidepressant drugs due to its ability to influence stereochemistry and metabolic stability in final drug molecules. Also utilized in the preparation of fluorinated analogs for structure-activity relationship (SAR) studies in medicinal chemistry. Its fluorine substituent enhances lipophilicity and bioavailability, making it valuable in optimizing drug candidates.
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