Used primarily for the precise determination of trace water content in substances, this reagent is essential in coulometric Karl Fischer titration. It is especially effective for samples with very low moisture levels, typically below 1%, such as solvents, active pharmaceutical ingredients, and fine chemicals. The presence of pyridine enhances stability and reaction efficiency, making it suitable for demanding analytical applications in pharmaceuticals, petrochemicals, and polymers. Its single-component formulation simplifies handling and reduces preparation time, ensuring consistent results in automated titration systems. Commonly used in quality control and research labs where high accuracy in moisture measurement is critical.