AK-1 is primarily used in research settings as a selective inhibitor of STAT3 signaling pathways. It is particularly valuable in studying the role of STAT3 in cancer biology, as it helps in understanding the mechanisms of tumor growth and survival. Researchers utilize AK-1 to explore potential therapeutic strategies for cancers that are driven by aberrant STAT3 activity. Additionally, it is employed in biochemical assays to investigate the effects of STAT3 inhibition on cellular processes such as apoptosis, proliferation, and immune responses. Its application extends to preclinical studies where it aids in evaluating the efficacy of targeting STAT3 in various disease models.