N-[2-[5-Amino-1-[6-(2,6-difluorophenoxy)-4-methylpyridin-3-yl]pyrazole-4-carbonyl]-5-methyl-1H-indol-6-yl]methanesulfonamide
98%
Reagent
Code: #220422
CAS Number
2055918-71-1
blur_circular Chemical Specifications
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Molecular Information
Weight
552.55 g/mol
Formula
C₂₆H₂₂F₂N₆O₄S
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Storage & Handling
Storage
2-8°C
description Product Description
Used in the treatment of autoimmune diseases such as rheumatoid arthritis and psoriasis due to its potent inhibition of Janus kinase (JAK) enzymes, particularly JAK1. This compound helps reduce inflammation by blocking signaling pathways involved in immune cell activation. It has shown efficacy in clinical trials for improving symptoms and slowing disease progression in patients unresponsive to conventional therapies. Its selectivity for JAK1 minimizes off-target effects, contributing to a more favorable safety profile compared to broader immunosuppressants.
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