Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for myeloproliferative disorders. Shows promising activity against JAK2-dependent cell lines, helping suppress abnormal cell proliferation. Also investigated for autoimmune diseases due to its role in modulating cytokine signaling pathways. Its structure allows for high binding affinity and improved metabolic stability, making it a valuable scaffold in optimizing kinase inhibitors.