1-​Piperidinecarboxylic acid,4-​[[5-​methyl-​3-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyrimidin-​7-​yl]​amino]​-​,1-​[(2E)​-​4-​(dimethylamino)​-​1-​oxo-​2-​buten-​1-​yl]​-​3-​pyrrolidinyl ester

95%

Reagent Code: #201710
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CAS Number 2326428-25-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 497.63 g/mol
Formula C₂₆H₃₉N₇O₃
inventory_2 Storage & Handling
Density 1.27±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

Used primarily in pharmaceutical research and development, this compound functions as a potent and selective inhibitor of Janus kinase 3 (JAK3), an enzyme involved in immune system signaling. Its main application lies in the treatment of autoimmune and inflammatory diseases such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. Due to its selectivity for JAK3 over other JAK family members, it offers potential for reduced side effects compared to broader JAK inhibitors. It is also investigated for use in organ transplantation to suppress immune rejection. The compound's structure allows for improved oral bioavailability and metabolic stability, making it suitable for once-daily dosing in clinical settings. Additionally, it serves as a valuable tool compound in biochemical assays to study JAK-STAT signaling pathways.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿6,940.00
inventory 50mg
10-20 days ฿32,620.00

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