N-Methoxy-N-methylisoxazole-3-carboxamide is a Weinreb amide derivative utilized in organic synthesis. It facilitates the selective formation of ketones through reaction with organometallic reagents such as Grignard or organolithium compounds, where chelation prevents over-addition and allows isolation of the desired product. This reagent is valuable in constructing complex organic molecules, particularly in pharmaceutical and bioactive compound synthesis, offering high efficiency and control in carbonyl group manipulation.