Imatinib-d8, a deuterated form of imatinib, is primarily used in research and development as an internal standard in mass spectrometry. Its application is crucial for the accurate quantification of imatinib in biological samples, such as blood or plasma, during pharmacokinetic studies. By using Imatinib-d8, researchers can achieve more precise and reliable measurements, which are essential for understanding drug metabolism and optimizing therapeutic dosages. Additionally, it aids in the development of analytical methods for quality control in pharmaceutical manufacturing, ensuring consistency and safety of imatinib-based medications.