Used extensively in biomedical research to study the role of 15(S)-HETE in various physiological and pathological processes. It serves as a stable isotope-labeled internal standard in mass spectrometry for accurate quantification of endogenous 15(S)-HETE levels in biological samples. This aids in understanding its involvement in inflammation, cancer, and cardiovascular diseases. Additionally, it is utilized in lipidomics studies to explore eicosanoid signaling pathways and their impact on cellular functions. The deuterated form ensures minimal interference with natural metabolic processes, making it a valuable tool for tracing and analyzing biochemical mechanisms.