This compound is primarily used in research and development as an isotopic-labeled internal standard in mass spectrometry-based assays. It aids in the quantitative analysis of regorafenib and its metabolites in biological samples, ensuring accuracy and precision in pharmacokinetic and pharmacodynamic studies. Its application is critical in drug development, enabling researchers to monitor drug levels, assess bioavailability, and understand metabolic pathways. Additionally, it supports clinical studies by providing reliable data for optimizing dosing regimens and evaluating therapeutic efficacy in cancer treatment.