Resolvin D2-d5 is primarily used in biomedical research to study inflammation and its resolution processes. It serves as a stable isotope-labeled analog of Resolvin D2, enabling researchers to track and quantify the compound's distribution, metabolism, and effects in biological systems. This makes it a valuable tool for understanding the mechanisms of inflammation resolution and developing therapeutic strategies for inflammatory diseases. Additionally, it is utilized in lipidomics studies to investigate the role of specialized pro-resolving mediators in promoting tissue repair and reducing chronic inflammation. Its application extends to preclinical studies, where it helps evaluate the efficacy of anti-inflammatory treatments.