Used as an internal standard in mass spectrometry-based bioanalytical studies to accurately quantify rivaroxaban levels in biological samples such as plasma or serum. Its primary application is in pharmacokinetic and metabolic studies, where it helps correct for variability in sample preparation and instrument response. Due to its deuterated structure, it closely mirrors the behavior of non-labeled rivaroxaban during analysis, ensuring high precision and reliability in drug monitoring and clinical research.