Used as a stable isotope-labeled internal standard in mass spectrometry and metabolic studies to accurately quantify L-asparagine in biological samples. Its 15N-labeled amide group allows researchers to trace nitrogen metabolism pathways in cells, particularly in cancer and neurological research where asparagine metabolism plays a key role. Also employed in protein synthesis studies and amino acid transport assays to distinguish endogenous versus exogenous asparagine. The monohydrate form ensures stability during storage and handling in analytical applications.