tert-Butyl (4-isothiocyanatobutyl)carbamate

95%

Reagent Code: #149114
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CAS Number 247035-47-8

science Other reagents with same CAS 247035-47-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 230.3271 g/mol
Formula C₁₀H₁₈N₂O₂S
badge Registry Numbers
MDL Number MFCD01862958
thermostat Physical Properties
Boiling Point 356.1ºC at 760 mmHg
inventory_2 Storage & Handling
Density 1.067 g/cm3 at 20 °C(lit.)
Storage 2-8°C, inert gas, dry, sealed

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its isothiocyanate group readily reacts with amines and other nucleophiles, enabling conjugation in drug design for targeted therapies. Commonly employed in the preparation of PROTACs (proteolysis-targeting chimeras) due to its ability to link E3 ligase ligands with target protein binders. Also utilized in chemical biology for labeling and probing protein interactions through covalent attachment. Stable under standard conditions and compatible with solid-phase synthesis, making it suitable for combinatorial chemistry and high-throughput screening applications.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿5,430.00
inventory 1g
10-20 days ฿14,660.00
inventory 5g
10-20 days ฿71,830.00

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tert-Butyl (4-isothiocyanatobutyl)carbamate
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its isothiocyanate group readily reacts with amines and other nucleophiles, enabling conjugation in drug design for targeted therapies. Commonly employed in the preparation of PROTACs (proteolysis-targeting chimeras) due to its ability to link E3 ligase ligands with target protein binders. Also utilized in chemical biology for labeling and probing pr

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its isothiocyanate group readily reacts with amines and other nucleophiles, enabling conjugation in drug design for targeted therapies. Commonly employed in the preparation of PROTACs (proteolysis-targeting chimeras) due to its ability to link E3 ligase ligands with target protein binders. Also utilized in chemical biology for labeling and probing protein interactions through covalent attachment. Stable under standard conditions and compatible with solid-phase synthesis, making it suitable for combinatorial chemistry and high-throughput screening applications.

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