tert-Butyl (4-isothiocyanatobutyl)carbamate
95%
science Other reagents with same CAS 247035-47-8
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its isothiocyanate group readily reacts with amines and other nucleophiles, enabling conjugation in drug design for targeted therapies. Commonly employed in the preparation of PROTACs (proteolysis-targeting chimeras) due to its ability to link E3 ligase ligands with target protein binders. Also utilized in chemical biology for labeling and probing protein interactions through covalent attachment. Stable under standard conditions and compatible with solid-phase synthesis, making it suitable for combinatorial chemistry and high-throughput screening applications.
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