Used primarily as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical research. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester derivatives. These transformations are commonly employed in the development of kinase inhibitors and other targeted therapies in medicinal chemistry. The fluorinated isoquinoline scaffold enhances binding affinity and metabolic stability in drug candidates, improving pharmacokinetic properties. It is also utilized in the preparation of fluorescent probes and labeling agents for biochemical assays due to its favorable electronic characteristics and reactivity profile.