6-fluoroisoquinoline is primarily used as a key intermediate in the synthesis of pharmaceuticals, especially in the development of kinase inhibitors and antimicrobial agents. Its structure allows for selective interactions with biological targets, making it valuable in drug discovery. It is also employed in the preparation of fluorescent probes and optoelectronic materials due to its electron-accepting properties and stability in various reaction conditions. Additionally, derivatives of 6-fluoroisoquinoline are explored in agrochemical research for developing new pesticides with improved efficacy and environmental profiles.