Efonidipine hydrochloride is primarily used as a calcium channel blocker in research for the treatment of hypertension. It works by relaxing the blood vessels, which helps to lower blood pressure and improve blood flow. This compound is particularly effective in managing high blood pressure in models unresponsive to other antihypertensive agents. Additionally, it is investigated for angina, as it helps to reduce the frequency and severity of chest pain by improving oxygen supply to the heart. Efonidipine hydrochloride is favored for its dual action on both L-type and T-type calcium channels, providing a broader therapeutic effect. It is applied in pharmaceutical research and development.