R()-IAA-94 is primarily used in scientific research as a selective inhibitor of chloride channels. It is particularly valuable in studying the role of these channels in various physiological processes, such as cell volume regulation, neuronal excitability, and transepithelial ion transport. Researchers utilize this compound to investigate its effects on chloride conductance in cells, helping to elucidate the mechanisms underlying diseases like cystic fibrosis, epilepsy, and hypertension. Its application extends to pharmacological studies, where it aids in the development of potential therapeutics targeting chloride channel dysfunction. Additionally, R()-IAA-94 is employed in electrophysiological experiments to analyze the biophysical properties of chloride channels and their interaction with other cellular components.