Yoda 1 is primarily utilized in scientific research, particularly in the study of mechanosensitive ion channels. It acts as a potent activator of Piezo1 channels, which are crucial for sensing mechanical forces in various biological processes. Researchers use Yoda 1 to investigate cellular responses to mechanical stress, such as in vascular biology, where it helps understand blood flow regulation and endothelial cell function. Additionally, it is employed in studies related to cell proliferation, differentiation, and tissue development, providing insights into diseases like hypertension and muscular dystrophy. Its application extends to drug discovery, where it serves as a tool to identify potential therapeutic targets for conditions involving mechanotransduction.