Used in organic synthesis as a hypervalent iodine reagent, particularly in oxidative cyclization and functionalization reactions. It enables efficient C–H activation and carbon–heteroatom bond formation under mild conditions. Commonly applied in the synthesis of heterocyclic compounds and natural products, serving as a versatile oxidant in place of heavy metal-based reagents. Its reactivity supports transformations in indole chemistry, including lactonization and ring closures, making it valuable in pharmaceutical and medicinal chemistry research.