Used in calibration of analytical instruments such as ion-selective electrodes and spectrophotometers for accurate measurement of fluoride concentrations in water, beverages, and industrial samples. Essential in environmental monitoring to ensure compliance with regulatory limits for fluoride in drinking water. Supports quality control in pharmaceutical and dental product manufacturing where fluoride levels must be precisely controlled. Also used in research and clinical labs for validating methods related to fluoride analysis in biological samples like urine and serum.