N-(cyclopropanesulfonyl)-4,4-dimethyl-2-[3-(morpholin-4-yl)phenyl]-1,2,3,4-tetrahydroquinoline-6-carboxamide
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Used in pharmaceutical research as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), this compound is investigated for its anti-inflammatory, analgesic, and neuroprotective properties. It shows promise in preclinical models for treating neuropathic pain, chronic inflammatory conditions, and certain cardiovascular diseases. Due to its ability to stabilize epoxy fatty acids, it modulates biological pathways involved in pain signaling and inflammation resolution. Its structural features enhance metabolic stability and blood-brain barrier penetration, making it suitable for central nervous system-targeted therapies. Currently, it serves primarily as a tool compound in mechanistic studies and as a lead structure for optimizing sEH inhibitors.
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