BAY 11-7082 is widely used in research settings to study inflammatory pathways and cellular signaling mechanisms. It is particularly valued for its ability to inhibit NF-κB activation, a key regulator of inflammation and immune responses. This makes it a useful tool in investigating diseases where NF-κB plays a critical role, such as cancer, autoimmune disorders, and chronic inflammatory conditions. Researchers also utilize it to explore the effects of NF-κB inhibition on cell survival, apoptosis, and gene expression. Its application extends to preclinical studies aimed at understanding potential therapeutic strategies targeting NF-κB signaling pathways.