4-Octyl Itaconate is widely recognized for its anti-inflammatory and antioxidant properties, making it a valuable compound in biomedical research and therapeutic applications. It is particularly studied for its role in modulating immune responses and reducing inflammation in various disease models, such as sepsis, arthritis, and neurodegenerative disorders. The compound activates the Nrf2 pathway, which enhances cellular defense mechanisms against oxidative stress and inflammation. Additionally, it has shown potential in improving metabolic health by regulating glucose and lipid metabolism. In dermatology, it is explored for its ability to protect skin cells from damage caused by UV radiation and environmental stressors. Its versatility and efficacy in targeting multiple biological pathways make it a promising candidate for developing treatments for chronic inflammatory and oxidative stress-related conditions.