L-701252 is a potent and selective antagonist of the leukotriene B4 (LTB4) receptor, primarily used in research settings to study inflammatory processes. It is applied in experimental models to inhibit neutrophil recruitment and activation, making it a valuable tool for investigating conditions driven by acute or chronic inflammation, such as arthritis, psoriasis, and respiratory diseases like asthma and COPD. Due to its high specificity, it helps clarify the role of the LTB4 pathway in immune responses without affecting related lipid mediators. Its use is largely confined to preclinical studies, where it aids in validating the therapeutic potential of targeting LTB4 signaling in inflammatory disorders.