L 651580 is primarily used in research settings as a potent and selective antagonist for the leukotriene D4 (LTD4) receptor. It has been investigated for its potential in studying inflammatory pathways, particularly those involved in asthma and other respiratory diseases. By blocking the action of LTD4, a mediator of bronchoconstriction and increased vascular permeability, L 651580 helps in understanding the role of cysteinyl leukotrienes in airway inflammation and hyperresponsiveness. Its application extends to preclinical models where modulation of leukotriene activity is required to assess therapeutic strategies for allergic and inflammatory conditions. Due to its specificity, it serves as a valuable tool in pharmacological studies aimed at developing new anti-inflammatory and anti-asthmatic agents.