APS-2-79 HCl
10mM in DMSO
Reagent
Code: #134352
CAS Number
2002381-31-7
blur_circular Chemical Specifications
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Molecular Information
Weight
423.89 g/mol
Formula
C₂₃H₂₁N₃O₃·HCl
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Storage & Handling
Storage
-20°C
description Product Description
Used as a potent and selective inhibitor of the NLRP3 inflammasome, this compound is applied in research settings to study inflammatory pathways associated with various diseases. It helps modulate the activation of NLRP3, which plays a key role in conditions such as Alzheimer's disease, type 2 diabetes, atherosclerosis, and autoimmune disorders. Due to its ability to suppress caspase-1 activation and interleukin-1β release, it is utilized in cellular and animal models to investigate the therapeutic potential of targeting inflammasome activity. Its application supports the development of anti-inflammatory drugs aimed at chronic and degenerative diseases driven by innate immune activation.
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