hPGDS-IN-1 is primarily used in research and development as a selective inhibitor of hematopoietic prostaglandin D synthase (hPGDS). This enzyme plays a significant role in the production of prostaglandin D2, which is involved in inflammatory and allergic responses. By inhibiting hPGDS, this compound helps in studying the pathways and mechanisms related to inflammation and allergic diseases. It is particularly useful in preclinical studies aimed at understanding the potential therapeutic effects of hPGDS inhibition in conditions such as asthma, atopic dermatitis, and other inflammatory disorders. Additionally, it serves as a valuable tool in the development of new anti-inflammatory and anti-allergic drugs.