3,3-difluoro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
98%
Reagent
Code: #89905
CAS Number
1613639-41-0
blur_circular Chemical Specifications
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Molecular Information
Weight
295.1 g/mol
Formula
C₁₄H₁₆BF₂NO₃
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Registry Numbers
MDL Number
MFCD22547891
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily in organic synthesis, this compound serves as a key intermediate in the development of pharmaceuticals, particularly in the creation of kinase inhibitors. Its boronate ester group enables efficient cross-coupling reactions, such as Suzuki-Miyaura reactions, which are crucial for constructing complex molecular architectures. Additionally, its indolin-2-one core is often exploited in the design of bioactive molecules targeting cancer and other diseases. The difluoro substitution enhances metabolic stability and binding affinity, making it valuable in drug discovery and medicinal chemistry research.
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