1-(tert-Butoxycarbonyl)indoline-2-carboxylic acid
96%
Reagent
Code: #148211
CAS Number
137088-51-8
blur_circular Chemical Specifications
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Molecular Information
Weight
263.29 g/mol
Formula
C₁₄H₁₇NO₄
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Registry Numbers
MDL Number
MFCD02682411
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Physical Properties
Boiling Point
411.6±44.0°C at 760 mmHg
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Storage & Handling
Density
1.259g/cm3
Storage
2-8°C, dry seal
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where indoline scaffolds are present. It serves as a protected form of indoline-2-carboxylic acid, allowing selective reactions at other functional groups during multi-step organic syntheses. Commonly applied in the preparation of protease inhibitors, kinase inhibitors, and other bioactive molecules in medicinal chemistry. Its Boc-protected amine group ensures stability and compatibility with various reaction conditions, making it valuable in solid-phase and solution-phase peptide-like couplings.
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