Hirsutine is an indole alkaloid found in plants of the Uncaria genus, such as Uncaria rhynchophylla. It is primarily explored for its potential therapeutic applications in medicine due to its diverse pharmacological properties. It has shown promise as an antiarrhythmic agent, helping to regulate irregular heartbeats by blocking calcium channels in cardiac cells. Additionally, hirsutine exhibits antiviral properties, particularly against influenza viruses, making it a candidate for antiviral drug development. Research also suggests its potential in managing hypertension through its ability to relax blood vessels via vasodilation. Furthermore, hirsutine has been studied for its neuroprotective effects, which could benefit treatments for neurodegenerative diseases. In traditional Chinese medicine, Uncaria species containing hirsutine are used for conditions like hypertension, headaches, and convulsions. Preliminary studies also indicate anti-inflammatory, antioxidant, and potential anticancer activities, including inhibition of cancer cell growth.