1-Boc-3-Bromo-5-methoxyindole

98%

Reagent Code: #45291
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CAS Number 348640-11-9

science Other reagents with same CAS 348640-11-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 326.19 g/mol
Formula C₁₄H₁₆BrNO₃
badge Registry Numbers
MDL Number MFCD05864762
thermostat Physical Properties
Boiling Point 403.846ºC
inventory_2 Storage & Handling
Density 1.379g/cm3
Storage Room temperature, dry, sealed

description Product Description

This compound is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the production of various biologically active molecules, including drug candidates and agrochemicals. The Boc (tert-butoxycarbonyl) group provides protection for the indole nitrogen during synthetic processes, allowing for selective reactions at other sites of the molecule. The bromine atom at the 3-position offers a reactive site for further functionalization through cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the introduction of diverse substituents. The methoxy group at the 5-position can influence the electronic properties of the indole ring, enhancing its reactivity or modulating the biological activity of the final product. This compound is particularly valuable in the synthesis of indole-based alkaloids, serotonin receptor ligands, and other heterocyclic compounds with potential therapeutic applications. Its versatility makes it a crucial building block in medicinal chemistry and drug discovery.

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Test Parameter Specification
Purity 97.5-100
Appearance Off-white powder

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,240.00
inventory 2g
10-20 days ฿10,060.00
inventory 500mg
10-20 days ฿2,590.00

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1-Boc-3-Bromo-5-methoxyindole
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This compound is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the production of various biologically active molecules, including drug candidates and agrochemicals. The Boc (tert-butoxycarbonyl) group provides protection for the indole nitrogen during synthetic processes, allowing for selective reactions at other sites of the molecule. The bromine atom at the 3-position offers a reactive site for further functionalizat

This compound is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the production of various biologically active molecules, including drug candidates and agrochemicals. The Boc (tert-butoxycarbonyl) group provides protection for the indole nitrogen during synthetic processes, allowing for selective reactions at other sites of the molecule. The bromine atom at the 3-position offers a reactive site for further functionalization through cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the introduction of diverse substituents. The methoxy group at the 5-position can influence the electronic properties of the indole ring, enhancing its reactivity or modulating the biological activity of the final product. This compound is particularly valuable in the synthesis of indole-based alkaloids, serotonin receptor ligands, and other heterocyclic compounds with potential therapeutic applications. Its versatility makes it a crucial building block in medicinal chemistry and drug discovery.

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